Fluid balance is important in maintaining homeostasis in our body. The fluid lost should be more or less equal to the amount of fluids taken. To replenish the fluids lost through respiration, perspiration, and urination we drinks fluids or we get it from the food we ingest.
Imbalances could happen in our body. We could have water retention due to disease processes. This is an alteration in our normal homeostasis. The main goal when we have conditions like this is to treat the underlying cause why there is water retention. Aside from this, we also may need to use drugs to promote diuresis.
Diuresis is defined as the augmented formation and elimination of urine. Certain drugs are also prescribed to produce diuresis for relief of certain conditions like hypertension and congestive heart failure.
There are different types of Diuretics and each has its own mechanism of action though they have the same effect and that is to promote diuresis. One common type are loop diuretics. An example of this is Furosemide 40mg.
The usual beginning oral Lasix dosage as a treatment for edema in adult clients is 20-80 mg. An increased dose or the same dose may be given 6-8 hours after. Lasix dosage may be increased 20-40 mg every 6-8 hours until the anticipated outcome occurs. The effective Lasix dosage may be administered once or twice daily. Doses more than 6 mg/kg are not suggested
However, we must remember that excessive diuresis can lead to dehydration and blood volume drop. This can lead to circulatory collapse especially in the geriatric population. This is especially true to patients receiving higher Lasix dosage with a restricted salt intake which is commonly recommended for patients taking this drug.
One the most common adverse effect of diuretics like Furosemide 40mg is potassium depletion in our body. Potassium together with sodium is excreted as well in the urine. With this concern, another class of diuretic called potassium sparing diuretics are used. To counteract the effect of Furosemide 40mg in relation to potassium levels in our blood, patients are given potassium supplements or they are encouraged to increase their diet with potassium rich foods such as banana, raisins, prunes, and orange juice.
Just like any other drug, we need to take Furosemide 40mg as prescribed by the doctor. Do not adjust your Lasix dosage on your own. Diuresis may continue for up to 6 hours after administration. Lasix dosage should be decreased after taking it for a few weeks. Tell your doctor if you experience muscle cramps, weakness, dizziness, confusion, thirst, blurred vision, headache while taking Furosemide 40mg.
Patients on diuretic therapy are also often placed on a salt-restricted diet. This is to make the therapy more effective. If there is more sodium in our body, there will also water retention.